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The limit of storage and even boredom also prove problematics, and for most of the voyage between worlds, the crew is placed into hypothermic coma, their blood replaced by a synthic, their metabolism slowed to a crawl.
In this state of near death, the crew member is suspended in a gel bath at near freezing with oxygen and nutrition provided by the sythetic fluid pumped into their bodies through a permanantly installed shunt leading to their circulitory system.
Hypothermic sleep is a relatively safe method of transport, although there are some occasional mishaps.